Cover photo for Caleb Rice Matthews, M.D.'s Obituary
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1991 Caleb 2022

Caleb Rice Matthews, M.D.

August 22, 1991 — November 11, 2022

Jacksonville Beach


Dr. Caleb Rice Matthews M.D., 31, passed away November 11, 2022, in Jacksonville Beach, Florida. He was born in Tifton, GA on August 22, 1991, and raised in his beloved state of Georgia.

Taking an early affinity for athletics and science, he accepted a soccer scholarship to Stetson University. After graduating with honors, he attended the University of Florida College of Medicine where he took a keen interest in Cardiothoracic Surgery. Subsequently, he was accepted into a highly competitive Integrated Cardiothoracic Surgery program at Indiana University. During his second year of residency, Caleb was diagnosed with a rare form of metastatic cancer.

Always the fighter, Caleb accepted this challenge with his characteristic smile and began a three-and-a-half-year battle for his life. During this time, Caleb continued his passion for medicine, publishing multiple scholarly articles and ultimately completing his memoirs in his book “Case Study: Me.”

Caleb is survived by his mom, Ricki Taylor (Ken), his father Joe Matthews (Amelia), brother Josh Matthews (Katie), sister Teal Matthews, Grandmother Lillian Matthews and his loving dog Hank.

In lieu of flowers or gifts, the family requests donations to be made to the Neuroendocrine Tumor Research Foundation ( to help others in their fight against the disease.

A Celebration of Caleb’s Life will be held at the Baughman Center (982 Museum Dr, Gainesville, FL 32603) on December 17th, at 6:30PM.

To order memorial trees in memory of Caleb Rice Matthews, M.D., please visit our tree store.


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